Elias Hossain
Hello! I’m Elias, a graduate student at Mississippi State University, USA, specializing in large language models (LLMs) with a focus on healthcare applications. My research centers on LLM reasoning and clinical uncertainty measurement, aiming to make AI-driven medical systems more interpretable, reliable, and safe. I’m particularly interested in how LLMs respond to ambiguous clinical scenarios, with the goal of enhancing trust and usability in real-world healthcare environments. In addition to uncertainty modeling, I’ve worked on conversational AI, including the development of BarkPlug, an LLM-based chatbot designed to help students easily access engineering department resources. I also contributed to an NIH-funded project in collaboration with the Psychology Department, where I applied machine learning to investigate age-related memory patterns. Earlier in my career, I gained nearly three years of experience in the software industry, where I focused on AI solutions in healthcare and built custom desktop, web, and Linux-based applications. I also developed speech-to-text (STT) and text-to-speech (TTS) systems for low-resource languages, contributing to accessibility-focused innovations. My journey began in Bangladesh, where I earned my bachelor's degree and started building mobile applications before modern AI tools were widely accessible. In 2017, I was honored to win the divisional championship in the NASA Space Apps Challenge for best use of NASA data—an early milestone that fueled my passion for research. For me, research is not just about publishing papers; it’s about solving meaningful problems that can make a real-world impact. I’m excited about what lies ahead and remain committed to advancing AI in healthcare and beyond.
Recent News
- Distinguished Speaker, 2nd Global Congress on Advanced Satellite Communications (Adv. Satellite 2024) event, London, United Kingdom
- Invited Speaker, Mississippi Health Innovation Conference 2024, Millsaps College in Jackson, United States
- Abstract Accepted, Frontiers in Education 2024 - Washington D.C., USA
Education
Mississippi State University, United States
Research
R-GAT: Residual Graph Attention Network for Biomedical Document Classification
This completed project proposes R-GAT, a Residual Graph Attention Network for classifying medical documents from the PubMed database. It encodes textual units as graph nodes and semantic relations as edges, effectively handling long-form biomedical texts across thyroid, colon, lung, and generic categories.
The model computes node representations using multi-head graph attention:
\[ h_i' = \sigma\left(\sum_{j \in \mathcal{N}(i)} \alpha_{ij} W h_j\right) \]
\[ \alpha_{ij} = \frac{\exp\left(\text{LeakyReLU}(a^T [Wh_i \, || \, Wh_j])\right)}{\sum_{k \in \mathcal{N}(i)} \exp\left(\text{LeakyReLU}(a^T [Wh_i \, || \, Wh_k])\right)} \]
Residual connections and global pooling improve training stability and classification performance. A version has been submitted as a preprint to arXiv.
LLM Reasoning: Enhancing Multi-Step Reasoning in Large Language Models
This ongoing project investigates the reasoning capabilities of Large Language Models (LLMs) in multi-hop and chain-of-thought tasks. We explore methods to inject structured reasoning using step supervision and logical consistency constraints.
We define a hybrid loss combining language modeling with reasoning consistency:
\[ \mathcal{L}_{\text{total}} = \lambda_1 \cdot \mathcal{L}_{\text{LM}} + \lambda_2 \cdot \mathcal{L}_{\text{reason}} \]
Here, \( \mathcal{L}_{\text{LM}} \) is the standard token prediction loss, and \( \mathcal{L}_{\text{reason}} \) ensures intermediate steps follow logical structure. We evaluate on datasets like GSM8K, MEDQA, and StrategyQA.
Contrastive Learning in Positive-Unlabeled Data with LLMs
This project explores the integration of contrastive learning with Large Language Models (LLMs) to enhance classification in Positive-Unlabeled (PU) settings, where only partial labels are available. The method learns discriminative representations by contrasting positive examples against ambiguous unlabeled data in embedding space.
We fine-tune a pretrained LLM using a contrastive loss that separates positive pairs from uncertain examples while preserving semantic alignment:
\[ \mathcal{L}_{\text{total}} = \lambda_1 \cdot \mathcal{L}_{\text{LM}} + \lambda_2 \cdot \mathcal{L}_{\text{cont}} \]
\[ \mathcal{L}_{\text{cont}} = -\log \frac{\exp(\text{sim}(z_i, z_j)/\tau)}{\sum_{k=1}^{K} \exp(\text{sim}(z_i, z_k)/\tau)} \]
Here, \( \text{sim}(z_i, z_j) \) denotes cosine similarity between representations, and \( \tau \) is a temperature parameter. This framework helps the LLM distinguish informative unlabeled instances without requiring full supervision.
Publications
Conferences
The Mississippi Innovation Health Conference was held at the historic Christian Center within Millsaps College in Jackson, United States, on 26 March 2024. This event showcased advancements in health informatics and featured presentations from industry experts. I was invited to present my research on AI in healthcare at this conference.

Talking about AI in Healthcare

Unveiling the Latest in Health Innovation

Navigating the Digital Health and Technology

Spotlight on My Poster Research: MIHC 2024

In Discussion with Dr. David, MSU Professor

Spring 2024 Graduate Research Symposium
Awards
4IR Skills Award (2023)
In recognition of notable contribution in 4IR skills, organized by North South University Career and Placement Center, in collaboration with Aspire to Innovate (a2i) and Thriving Skills.
DIU Research Award (2021)
For scholarly publication in reputed indexed journals (2019–2021), awarded by the Division of Research, Daffodil International University, Bangladesh.
Innovation Awards Finalist (2019)
Finalist at Dr. Pradeep P Thevannoor Innovation Awards (PPTIA), organized by SCMS School of Engineering and Technology (SSET), Kerala, India.
Champion – UAP Carnival (2018)
Best Innovative Mobile Application Development category, University of Asia Pacific (UAP) Software and Hardware Carnival.
National Winner – SS12 Innovation Challenge (2018)
Organized by IEEE Bangladesh Section and Humanitarian Activity Committee (HAC), held at Independent University Bangladesh.
NASA Space Apps Champion (2017)
Division Champion on Best Use of NASA Data Resources, organized by Bangladesh Association of Software and Information Services (BASIS). [View Project]