I am a Doctoral researcher in the Complex Adaptive Systems Lab at the University of Central Florida, advised by Dr. Niloofar Yousefi. My research is about reliable LLMs when humans can't supervise at scale. Three concrete questions drive the work. (1) Can pretrained transformers report calibrated uncertainty in their own attention? (2) Can we verify AI-generated supervision when the judges themselves share blind spots? (3) Can we monitor tool-using agents and intervene on unsafe trajectories, not just outputs? One constraint runs through all three: the method has to work on a model I cannot retrain, since that is the access most deployed systems allow. So the work is inference-time or training-free, tested under adversarial input and distribution shift. I also build language models from scratch, which changes what you believe about how they fail. My applied vertical is clinical and biomedical AI, where the cost of confident errors is measured in patient harm, not benchmarks.

  1. Test-Time Uncertainty in Pretrained Transformers
    • Uncertainty-aware attention at inference time, without retraining.
    • Confidence calibrated enough to route clinical cases to a human.
    • Abstain under a fixed risk budget rather than answer every input.
  2. Reliable AI Supervision
  3. Runtime Safety and Evaluation for LLM Agents
    • Inspect an agent's plan, then allow, block, confirm, or revise.
    • Gate inter-agent channels so poisoned output carries no instructions.
    • Score the trajectory a clinical agent takes, not just its answer.

Conferences and talks

Invited talk on AI in healthcare at the Mississippi Health and Innovation Conference, 2024
Mississippi Health & Innovation Conference, 2024
Invited talk on AI in healthcare and what it can mean for rural America.
Mississippi Health and Innovation Conference, 2024: With Professor David.
Mississippi Health & Innovation Conference, 2024
With Professor David.
MoML 2025, MIT: Molecular Machine Learning Conference, Cambridge.
MoML 2025, MIT
Molecular Machine Learning Conference, Cambridge.
MoML 2025, MIT: Molecular Machine Learning Conference, Cambridge.
MoML 2025, MIT
Molecular Machine Learning Conference, Cambridge.
MoML 2025, MIT: Molecular Machine Learning Conference, Cambridge.
MoML 2025, MIT
Molecular Machine Learning Conference, Cambridge.

Who I work with

13Institutions
5Countries
4Continents
6Industry Labs

I work with researchers who have led or built AI at Meta, Google AI, Intel, Amazon, GE Research, and audEERING — alongside academic and clinical groups on four continents.

SL
Tenured Associate Professor, Computer Science · University of Central Florida
Senior Research Scientist Manager, Facebook AI / Meta · 2018–2023 Director, GE Research h-index 58 19,000+ citations Joint project: CorrFilter →
BS
Professor, TU München and Imperial College London · CSO, audEERING
h-index 129 · 87,000+ citations Affective computing Computer audition
Assistant Professor and Faculty Fellow, Center for Data Science · New York University
Formerly Google AI and Intel · information-theoretic deep learning
Professor, University of Southern Queensland, Australia
Speech and affective computing
Associate Professor, Institute for Artificial Intelligence · University of Central Florida
Foundation models and healthcare AI
Associate Professor, Pediatrics · Nemours Children’s Health
Pediatric emergency and clinical research
Queensland University of Technology, Australia
Clinical NLP and remote patient monitoring
Shubhashis Roy Dipta
University of Maryland, Baltimore County
Applied Scientist Intern, Amazon · NLP and reasoning
UCF TU München Imperial College London New York University UMBC Univ. of Southern Queensland Purdue Fort Wayne Mississippi State Meharry Medical College North South University Queensland Univ. of Technology Nemours Children’s Health AUST

Advised at UCF by Dr. Niloofar Yousefi and Dr. Ivan Garibay.

Featured Publications

Check out Google Scholar for a full list of my publications.

MPV pipeline: raw preference data passes through four verifier agents, a k-of-n consensus filter, and into a verified preference dataset used for DPO training Full figure

Fault-Tolerant Preference Alignment via Multi-Agent Verification

E. Hossain, M. Rahimimovassagh, S. Neupane, M. J. I. Basher, I. Garibay, N. Yousefi
ICLR 2026 Workshop on Principled Design for Trustworthy AI

RLHF and DPO both assume the preference data is trustworthy. MPV drops that assumption: four verifier agents check every preference pair for factuality, safety, ethics, and trust, and only pairs clearing a k-of-n vote reach training. Consensus provably suppresses corrupted supervision at an exponential rate, and on Qwen2-7B it cuts the summarization refusal rate from 0.148 to 0.005 while holding win-rate at parity.

ChannelGuard system diagram: the threat surface, a multi-agent pipeline with six information-bottleneck gates, and the pass, compress, or block decision made at each gate Full figure

ChannelGuard: Safe Models Do Not Compose into Safe Multi-Agent Systems

E. Hossain, M. M. H. Nipu, F. T. J. Faria, T. N. Ornee, M. Sheikh
Preprint, 2026

Across 2,100 test cases and eight attack families, the apparent safety of multi-agent LLM pipelines often rests on opaque provider filters rather than the system itself. ChannelGuard places training-free information-bottleneck gates on every inter-agent channel, blocking tool-output poisoning outright and halving prompt-injection success while holding task accuracy at 0.867.

NEXUS architecture: tool-using LLM agents emit a structured plan that a runtime safety monitor screens with deterministic rules, argument inspection, a learned risk score, and a session manager before issuing one of four graded interventions Full figure

NEXUS: Structured Runtime Safety for Tool-Using LLM Agents

E. Hossain, M. M. H. Nipu, T. N. Ornee, R. Rana, N. Yousefi
Preprint, 2026

A structured-plan safety monitor that chooses among four interventions, allow, block, request confirmation, or request revision, by combining deterministic rules, argument-level inspection, and a calibrated risk score for graded escalation. Reaches 0.949 F1 while adding 0.205 ms median latency, under 0.1% overhead on a typical agent loop.

UAT-LITE architecture: Bayesian embedding calibration, uncertainty-weighted attention, MC-dropout uncertainty estimation, and a confidence-guided decision module Full figure

UAT-LITE: Inference-Time Uncertainty-Aware Attention for Pretrained Transformers

E. Hossain, S. R. Dipta, S. Neupane, R. Rana, R. Shwartz-Ziv, I. Garibay, N. Yousefi
ACL ARR meta-review: borderline conference accept · committing to EMNLP 2026

Inference-time method that uses Monte-Carlo dropout to make pretrained transformer attention uncertainty-aware. Improves calibration, selective prediction, and robustness without retraining.

Safe and Scalable Collaboration in Multiagent LLM Systems: A Comprehensive Review

E. Hossain, M. M. H. B. Nipu, M. S. Mahmood, M. J. Hossen, M. F. Mridha
IEEE Transactions on Systems, Man, and Cybernetics: Systems, 2026

A review of large language model based multiagent ecosystems, covering how agents coordinate, communicate, and reason across distributed settings, and what fails as those systems scale. Organized around four foundational pillars of multiagent LLM design, it maps the safety and scalability gaps that separate working demonstrations from deployable systems.

BIOGEN architecture: RNA-seq gene clusters pass through a retrieval layer over PubMed and UniProt, an interpreter agent, a critic ensemble with a consensus layer, and a persistent context memory before biological interpretation is produced Full figure

BIOGEN: Evidence-Grounded Multi-Agent Reasoning for Transcriptomic Interpretation in Antimicrobial Resistance

E. Hossain, M. Shoeibi, I. Garibay, N. Yousefi
Frontiers in Bioinformatics, vol. 6, 2026

A multi-agent framework that interprets RNA-seq gene clusters by pairing retrieval over PubMed and UniProt with an interpreter agent and a three-way critic ensemble. Every claim carries a verifiable identifier: the non-verifiable identifier rate is 0.000 against 0.100 for an LLM-only baseline, and BIOGEN is the only system holding that rate at zero across all five bacterial datasets, including under cross-organism and cross-condition shift.

Parametric temporal conflict overview: a frozen LLM baseline returning the outdated fact, conflict localization by comparing standard and date-prefixed prompts, and residual-stream steering that recovers the newer fact Full figure

Right Knowledge, Wrong Answer: Characterizing Parametric Temporal Conflict in Open-Weight Language Models

E. Hossain, S. Saha, T. N. Ornee, S. S. Jennifer, U. C. Biswas, S. R. Dipta, R. Rana, N. Yousefi
Preprint, 2026

Introduces Parametric Temporal Conflict, where a model holds the newer fact but its default forward pass still prefers the outdated one. On a verified benchmark of 8,746 Wikidata transitions, a date-prefix prompt recovers the newer fact in 61–81% of cases and activation patching flips 72–85%, localizing the preference to model-specific upper layers rather than missing knowledge.

Certifications

2023
AI for Medicine Specialization — DeepLearning.AI on Coursera. Three-course track covering medical diagnosis, prognosis, and treatment-effectiveness prediction with deep learning. Verify
2022
IBM Professional Data Science Certificate — Coursera. End-to-end data science workflows: statistical modeling, machine learning with Python, and production pipelines. Verify

Projects

🛡️
2026

SAVe V.1

Multi-agent safe alignment verification for preference-based LLM optimization. Presented as a poster at the Amazon Trusted AI Symposium, JFK 27, New York.

🧠
2025

MiniHealthLM

Lightweight, secure transformer language model trained from scratch for healthcare text. GitHub

📊
2025

mldriguard

Python package for detecting and mitigating data drift in machine learning models. GitHub

💊
2025

MedXpert

AI-powered drug discovery and comparison system. GitHub

Awards / Recognition

2025
Graduate Presentation Fellowship, UCF. Selective award funding research presentation at MIT.
2019
Finalist, Dr. Pradeep P. Thevannoor Innovation Awards, India.
2023
Award, Fourth Industrial Revolution Skills Summit, North South University (NSU).
2018
Winner, IEEE SS12 Innovation Challenge & Maker Fair, for the Kidnap Prevention Mobile App.
2017
Divisional Champion & Global Nominee, NASA Space Apps Challenge, for the Drone for Green Project.